ADALTIS Italia S.p.A.
March 21, 2008 — healthVia Cristoni, 12
40033 Casalecchio di Reno / BO
Italy
Phone: (+39-051)6136511
Fax: (+39-051)575280
http://www.adaltis.com
info.italia@adaltis.com
Company Figures
Number of employees 100-499
Area of business Laboratory Equipment
Diagnostics
Company Profile
Company File
Adaltis is an international in-vitro diagnostic company that develops, manufactures and markets in-vitro diagnostic systems and reagent products to detect viral infections, diagnose immune system diseases, and measure human hormone responses.
Adaltis offers a large and reliable product offering. Its long-standing expertise in the infectious disease, fertility and thyroid fields has translated into quality reagents that laboratories around the world have trusted for years.
Product Information
02.01 Analyser appliances
02.01.05 Automatic pipetting and diluting station
03.01.06 Electrolytes (without electrodes)
03.01.08 Devices and systems for glucose determination units
03.01.10 Devices and systems for haemoglobin determination
03.01.14 Rapid tests - clinical chemistry
(DOA) Amphetamine Surface Wipe Test
Amphetamines (amphetamine, methamphetamine, and the structurally related “designer” drugs, e.g., “Ecstasy”) are sympathomimetic amines whose biological effects include potent central nervous system (CNS) stimulation, anorectic, hyperthermic, and cardiovascular properties. They are usually taken orally, intravenously, or by smoking. Amphetamines are readily absorbed from the gastrointestinal tract and are then either deactivated by the liver or excreted unchanged in the urine. Amphetamines increase the heart rate and blood pressure and suppress the appetite. Some studies indicate that heavy abuse may result in permanent damage to certain essential nerve structures in the brain. Screening tests for drugs of abuse range from simple immunoassay tests to complex analytical procedures. The speed and sensitivity of immunoassays have made them the most widely accepted method for screening surfaces for drugs of abuse. The EASY LINE AMP WipeTest is based on the principle of the highly specific immunochemical reactions of antigens and antibodies.
(DOA) Barbiturates Surface Wipe Test
Barbiturates are a class of central nervous system depressants. Phenobarbital is a long acting barbiturate derivative that has been used as a daytime sedative and very extensively as an anticonvulsant. Pentobarbital and Secobarbital are two examples of short acting barbiturate sedatives. Abuse of barbiturates can lead not only to respiratory collapse, coma and even death. Barbiturates are taken orally, rectally, or by intravenous and intramuscular injection. Short acting barbiturates will generally be excreted in urine as metabolites, while the long-acting barbiturates will primarily appear unchanged.Screening tests for drugs of abuse range from simple immunoassay tests to complex analytical procedures. The speed and sensitivity of immunoassays have made them the most widely accepted method for screening for drugs of abuse. The EASY LINE Drug Screen BAR is based on the principle of the highly specific immunochemical reactions of antigens and antibodies which are used for the analysis of specific compounds in biological fluids and surfaces. This test is a rapid, visual, competitive immunoassay that can be used for the qualitative detection of barbiturates at 300 ng/mL cut-off concentration.
(DOA) MDMA Surface Wipe Test
Methamphetamine, amphetamine, and metabolites are potent sympathomimetic agents. Acute higher doses lead to enhanced stimulation of the central nervous system and include euphoria, alertness, and a sense of increased energy and power. More acute responses produce anxiety, paranoia, psychotic behavior, and cardiac dysrhythmias. The pattern of psychosis which may appear at high doses may be indistinguishable from schizophrenia. Screening tests for drugs of abuse range from simple immunoassay tests to complex analytical procedures. The speed and sensitivity of immunoassays have made them the most widely accepted method for screening surfaces for drugs of abuse. The EASY LINE MDMA WipeTest is based on the principle of the highly specific immunochemical reactions of antigens and antibodies which are used for the analysis of specific compounds in biological fluids. This test is a rapid, visual, competitive immunoassay that can be used for the qualitative detection of methamphetamines on surfaces at 1000 ng/ml cut-off concentration.
(DOA) Methamphetamines Surface Wipe Test
Methamphetamine, amphetamine, and metabolites are potent sympathomimetic agents. Acute higher doses lead to enhanced stimulation of the central nervous system and include euphoria, alertness, and a sense of increased energy and power. More acute responses produce anxiety, paranoia, psychotic behavior, and cardiac dysrhythmias. The pattern of psychosis which may appear at high doses may be indistinguishable from schizophrenia. Methamphetamine is excreted in urine as amphetamine and oxidized as deaminated and hydroxylated derivatives. However, 40% of meth-amphetamine is excreted unchanged. Thus the presence of the parent compound in the urine indicates methamphetamine use. Screening tests for drugs of abuse range from simple immunoassay tests to complex analytical procedures. The speed and sensitivity of immunoassays have made them the most widely accepted method for screening surfaces for drugs of abuse. The EASY LINE MET WipeTest is based on the principle of the highly specific immunochemical reactions of antigens and antibodies which are used for the analysis of specific compounds in biological fluids. This test is a rapid, visual, competitive immunoassay that can be used for the qualitative detection of methampheta
(DOA) Muldi Drug 5
The EASY LINE Drug Screen Multi 5-6 Device Test detects the most frequently used drugs simultaneously. In this connection, the cut-off is adjusted to the demands of the American National Institute on Drug Abuse (NIDA). Urine based screening tests for drugs of abuse range from simple immunoassay tests to complex analytical procedures. The speed and sensitivity of immunoassays have made them the most widely accepted method for screening urine for drugs of abuse. The EASY LINE Drug Screen Multi 5-6 Device Test is based on the principle of the highly specific immunochemical reactions of antigens and antibodies which are used to detect drugs and its metabolites in human urine. This assay provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the National Institute on Drug Abuse (NIDA). Clinical consideration and professional judgement should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated. The assay should not be used without proper supervision and is not intended for over the counter sales to lay persons. It is only for professional use.
03.02.01 Allergies
03.02.03 Auto-immune diseases
03.02.04 Fertility/Pregnancy hormones/Proteins
Eclectica DHEA-S
The Eclectica DHEA-S assay for the Eclectica analyzer has been designed for the quantitative determination of Dehydroepiandrosterone Sulphate in human serum and heparinised plasma.
Eclectica Estradiol
Estradiol (E2) is a steroid hormone with a molecular weight of 272.4 Dalton. It is composed of 18 carbon units and it is the most active estrogen hormone. The synthesis of E2 occurs mainly in the ovary, moreover small amounts of E2 are synthesized by adrenal cortex and by testis, or by periferal conversion of Testosterone. For these reasons also during the menopause, when ovary function is altered and as well in the man, circulating E2 is detectable, even if in small aliquots. The main biosynthetic pathway goes through D4-androstenedione and estrone which is converted in estradiol. In woman, during the normal menstrual cycle, the thecal cells of the developing and ripe Graafian follicle secrete estradiol into follicular antrum and into ovarian vein.
Eclectica FSH
Follicle-stimulating hormone (FSH, follitropin) is a 33 kDa glycoprotein hormone secreted by the anterior pituitary gland. The intact FSH molecule is noncovalently-linked dimer containing alpha and beta subunits. The FSH alpha subunit is homologous to the alpha subunits of several other glycoprotein hormones, including luteinizing hormone (LH), thyroid-stimulating hormone (TSH) and human chorionic gonadotropin (hCG). However, each hormone has a unique beta subunit. Both LH and FSH production and secretion are stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH release is normally pulsatile, resulting in episodic release of both FSH and LH. FSH production and secretion are regulated by a complex balance of endocrine feedback systems involving a number of steroid (estrogen, testosterone and progesterone) and peptide (inhibins, activins, follistatin) hormones. FSH is cleared by both hepatic and renal mechanisms.
Eclectica Free Estriol
During pregnancy, estriol production is predominantly from the foetal/placental unit. It is released from the placental and is conjugated in the maternal liver as glucuronides and sulphates. It exists in the maternal blood unconjugated (8%) and in conjugated forms (92%). Maternal serum unconjugated estriol levels increase rapidly following the first trimester from 1.2 ng/ml at 15 weeks to about 12 ng/ml at term. Measurement of serum unconjugated estriol can therefore be useful to monitor foetal conditions. Consistently low levels of estriol throughout pregnancy, or a sudden drop of estriol levels in serial determination may be indicative of foetal distress or placental failure. Chronically low estriol values may be caused by other factors unrelated to foetal distress or placental failure. Significantly low levels of unconjugated estriol in pregnancy have been shown to be associated with Down’s Syndrome. When combined with other parameters (hCG, AFP, maternal age, ethnic origin, gestational age) unconjugated estriol has been proposed as a screening test for Down’s Syndrome pregnancies.
Eclectica LH
Luteinizing Hormone (LH, lutropin) is a 29.4 kDa glycoprotein secreted by the anterior pituitary gland. The intact LH molecule is noncovalently-linked dimer containing alpha and beta subunits. The LH alpha subunit is homologous to the alpha subunits of several other glycoprotein hormones, including follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH),and human chorionic gonadotropin (hCG). However, each hormone has a unique beta subunit. Both LH and FSH production and secretion are stimulated by gonadotropin-releasing hormone (GnRH) from the hypothalamus. GnRH release is normally pulsatile, resulting in episodic release of both LH and FSH. LH production and secretion are regulated by a complex balance of endocrine feedback systems involving a number of hormones, including estrogen and progesterone.
03.02.05 Units and systems for hormone determination
03.02.07 Immuno assay systems
03.02.07.04 Clone-enzyme directed immunoassay (CEDIA)
03.02.07.07 FIFA technology (fluorescent immunofocus assay)
03.02.07.12 Immunoassay with particle count
03.02.08 Units and systems for the determination of immunoglobulins and plasma proteins
03.02.09 Individual and specified hormones
03.02.12 Rheumatoid diseases
03.05.01 Bacteriology - Infectious immunology
03.05.02 Hepatitis Viruses
03.05.03 Equipment and systems for HIV determination units
03.05.05 Equipment and systems for microbiological diagnosis/virology
03.05.06 Parasitology (Infectious immunology)
03.05.07 Retroviruses
03.05.08 Rapid tests - Infectious immunology